News Articles and Press Releases
April 2012
Zacharon Pharmaceuticals Enters Into Agreement with Acorda Therapeutics to Develop Small Molecules Targeting Spinal Cord Injury
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July 2011
Zacharon Pharmaceuticals and ARUP Laboratories Establish Partnership to Commercialize the Sensi-Pro™ Assay for Lysosomal Storage Diseases.
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April 2011
Zacharon Announces Collaboration with Pfizer to Develop Drugs for Multiple Rare Diseases
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January 2011
Zacharon and Mayo Clinic Enter Collaboration to Develop Clinical Diagnostics Based on Zacharon's Breakthrough Assay Technology
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November 2010
Zacharon Presents Preclinical Data on Lead Cancer Programs at the National Cancer Institute Investor Forum.
November 2010
Zacharon Awarded Nearly $1 Million in Grant Funding Through the Qualifying Therapeutic Discovery Project Tax Grant Program.
June 2010
Zacharon Presents Key Data on Lead Therapeutic Program at the 11th International Symposium in Mucopolysaccharide & Related Diseases.
December 2009
Zacharon Pharmaceuticals Emerging Company Profile published in
Start-Up
December 2008
Zacharon Pharmaceuticals Targets Glycans with Small Molecules (BioWorld)
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November 2008
Zacharon Pharmaceuticals Completes $3.5 Million Series A Financing and Receives More Than $2.2 Million in NIH Grants
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Scientific Publications and Papers
Xiaomei Bai, et. al., Novel Approach for Treating Neural Crest Derived Tumors: Selective Inhibition of Ganglioside Biosynthesis With Small Molecules. AACR 102nd Annual Meeting 2011.
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Ganglioside Inhibitor Program White Paper
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Mucopolysaccharidosis I, II, and III Program White Paper
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Brown JR, et. al., Small Molecule Inhibitors of Glycosaminoglycan Biosynthesis as a Substrate Optimization Therapy for the Mucopolysaccharidoses. Lysosomal Disease Network WORLD Symposium 2011.
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Xiaomei Bai, et. al., Small Molecule Inhibitors of Ganglioside Biosynthesis as a Substrate Reduction Therapy for the Gangliosidoses. Lysosomal Disease Network WORLD Symposium 2011.
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Brown JR, et.al., Glycan-Based Biomarkers for Lysosomal Storage Disease: The Sensi-Pro� Assay.
Lysosomal Disease Network WORLD Symposium 2010.
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Brown JR, Crawford BE, Esko JD.
Glycan Antagonists and Inhibitors: a Fount for Drug Discovery.
Crit Rev Biochem Mol Biol 2007; 42(6), 481-515. PMID: 18066955
Brown JR, Fuster MM, Li R, Varki N, Glass CA, Esko JD. 2006.
A Disaccharide-Based Inhibitor of Glycosylation Attenuates Metastatic Tumor Cell Dissemination.
Clin Cancer Res 2006; 12(9), 2894-901. PMID: 16675586
Brown JR, Fuster MM, Whisenant T, Esko JD.
Expression Patterns of ?2,3-Sialyltransferases and ?1,3-Fucosylatransferases Determine the Mode of Sialyl Lewis X Inhibition by Disaccharide Decoys.
J Biol Chem 2003; 278 (26), 23352-23359. PMID: 12686549